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Clinical outcomes and prognostic factors of salvage treatment for local lymph node recurrence after radical resection of oesophageal carcinoma

Cancer Management and Research Jul 29, 2021

Gu L, Liu Y, Ye H, et al. - In this retrospective study, researchers sought to assess clinical outcomes and prognostic factors related to the use of chemoradiotherapy (CRT) or radiotherapy (RT) for lymph node (LN) recurrence after curative resection of oesophageal squamous cell carcinoma (ESCC). Between 2014 and 2017, 117 ESCC patients with LN recurrence after radical resection receiving salvage treatment at our hospital were retrospectively reviewed. The 1-, 2- and 3-year overall survival (OS) rates were 75.2%, 40.2% and 27.4%, respectively, with a median follow-up of 19 months. Data reported that the median survival time was 19.0 months. Salvage CRT or RT was found to be both safe and effective in treating LN recurrence after ESCC radical resection. Patients with a small LN Max diameter (≤ 28 mm) who responded to salvage therapy appeared to have a long-term OS.

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