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Clinical observation of noncoronary cardiac abnormalities in Chinese children with Kawasaki disease

European Journal of Clinical Investigation Mar 24, 2020

Liu FF, Liu HH, Qiu Z, et al. - Researchers conducted the study for analyzing the clinical observation of noncoronary cardiac abnormalities in Chinese children (n = 142) with Kawasaki disease (KD). Participants in the study were recruited from July 2015 to April 2018. Blood samples were obtained at 24 hours pre‐intravenous immunoglobulin (IVIG) therapy. In patients with IVIG‐nonresponsive KD when compared with their IVIG‐responsive counterparts, plasma white blood cell counts were significantly increased. No major variations were found in the clinical classification distribution and the response to IVIG therapy regardless of whether or not NCA exhibited. Noncoronary cardiac abnormalities in acute KD are almost universal and manifest primarily as valvular regurgitation. This does not, however, affect the clinical classification and the response to IVIG therapy.

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