Derespina KR, Kaushik S, Plichta A, et al. - Researchers aimed at describing the clinical manifestations and outcomes of critically ill children with coronavirus disease-19 (COVID-19) in New York City via performing a retrospective observational study of children 1 month to 21 years who were admitted from March 14 to May 2, 2020 to 9 New York City pediatric intensive care units (PICUs) with SARS-CoV-2 infection. Admission of 70 children was reported to PICUs (median age 15 [IQR 9, 19] years; 61.4% male; 38.6% Hispanic; 32.9% Black), of these, 74.3% had comorbidities. Among these patients, severe sepsis developed in 12 patients (17%); vasopressor support was required in 14 (20%) patients; acute respiratory distress syndrome (ARDS) developed in 21 (30%) patients; acute kidney injury in 9 (12.9%) patients; 1 (1.4%) patient needed renal replacement therapy, and 2 (2.8%) had cardiac arrest. Hydroxychloroquine was used for treating 27 (38.6%) patients; remdesivir for 13 (18.6%); corticosteroids for 23 (32.9%); tocilizumab for 3 (4.3%) ; anakinra for 1 (1.4%) patient. Findings here suggest that predominantly adolescents comprise the critically ill children with COVID-19; further, these patients frequently have comorbidities, and require some form of respiratory support. Prolonged PICU and hospital stay were reported in significant correlation with the presence of acute respiratory distress syndrome.