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Clinical implications of tumor-associated tissue eosinophilia in tongue squamous cell carcinoma

The Laryngoscope Apr 25, 2019

Paz DD, et al. - Researchers investigated the possible role of tumor-associated tissue eosinophilia (TATE) in tongue squamous cell carcinoma (TSCC) in 259 subjects in this retrospective case series. They observed that greater levels of TATE were significantly correlated with male sex, alcohol consumption, cigarette smoking, higher pT classification, advanced disease stage, and tumor depth. They found the extranodal extension, cell differentiation, and TATE as independent predictors of overall survival and disease-free survival. The c-index of nomogram for overall survival was 0.786 indicating better accuracy in prognosis prediction than the TNM stage only (c-index = 0.738).
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