Collada JM, Castrejon I, Perez M, et al. - This study was attempted to assess the effect of musculoskeletal ultrasound (MSUS) in the management of rheumatoid arthritis (RA) patients and to evaluate factors affecting treatment strategy by the referring rheumatologist. A prospective study was conducted to examine RA patients at an MSUS clinic over a 6‐month period. They examined pre‐and-post‐MSUS follow‐up of 3 months of data. Individuals were categorized into 2 groups based on the decision of the referring rheumatologist to change the treatment after the MSUS examination. In a univariate analysis, comparisons between groups were conducted. Factors associated with changes in clinical management were investigated using logistic regression models. The study enrolled a sum of 64 RA patients. For MSUS examination, disease activity assessment is the most common indication, with the presence of power Doppler (PD) the factor most frequently correlated with changes in therapeutic management. The data indicate the effect of MSUS, particularly the use of PD, to support treatment decisions in RA routine care.