Balinotti JE, Maffey A, Colom A, et al. - Researchers sought to report the clinical course, infant pulmonary function tests and computed tomography (CT) findings in a cohort of patients with neuroendocrine cell hyperplasia of infancy (NEHI), which is one of the most common interstitial lung diseases in children. This observational multicenter cohort study was performed including 20 patients. Onset of symptoms was reported at the median age of 3 months and the diagnosis was made at median age of 6 months. Tachypnea, retractions and hypoxemia are the most common clinical presentations. Central ground glass opacities and air trapping are the recorded chest CT findings. The diagnosis was allowed by the typical clinical, CT and functional findings without the need of a lung biopsy. A Seventy-five percent of the cases (10/12) exhibit an obstructive pattern in infant pulmonary function tests. Although home oxygen therapy was required in most patients for 17 months, they showed a favorable evolution..