Dai J, et al. - Researchers probed the clinical features, risk factors and outcomes of patients with interstitial pneumonia with autoimmune features (IPAF). Raynaud’s phenomenon and ANA ≥ 1:320 were the most common systemic symptom and serological abnormality in IPAF cohort. Nonspecific interstitial pneumonia (NSIP) was the most frequent high-resolution computed tomography (HRCT) pattern. They noted an independent association of several factors including age, smoking history, organizing pneumonia (OP) pattern in HRCT, and anti-RNP positivity with significantly worse survival. Compared with other groups of interstitial lung disease (ILD), IPAF had the distinct clinical features and outcomes.