Faith EF, Shah S, Witman PM, et al. - In this retrospective, multicenter cohort study involving 436 patients, researchers sought to explore treatment interventions used for ulceration in infantile hemangioma (IH) and identify clinical prognostic indicators of healing time. Patients receiving care at tertiary referral centers assessed between 2012 and 2016 were involved; statistical and data analysis were conducted from February 7 to April 27, 2020. Local (wound care, topical), systemic (β-blocker, corticosteroids), and procedural (pulsed-dye laser) interventions were used to treat ulceration in IH. Despite the use of β-blockers, a subset of patients with IH ulceration continued to have prolonged IH healing times, according to this cohort study. Larger IH size seems to be a poor prognostic factor for time to heal. Propranolol should be started at lower doses (≤ 1 mg/kg/d) in patients who require systemic therapy.