Clinical features of transverse myelitis associated with systemic lupus erythematosus
Lupus Apr 22, 2020
Zhang S, Wang Z, Zhao J, et al. - In this research, the clinical characteristics and prognostic factors of systemic lupus erythematosus with transverse myelitis (SLE-TM) were distinguished in a relatively large patient series. Between 1993 and 2018, A retrospective study was conucted to include 45 SLE-TM individuals who treated as inpatients and outpatients at Peking Union Medical College Hospital. Researchers compared SLE-TM patients with 180 controls, and further compared SLE-TM patients with neuromyelitis optica spectrum disorder (NMOSD) with those without NMOSD. The data indicated that disease characteristics differed between SLE-TM patients with and without NMOSD. It was noted that SLE and NMOSD tended to be co-morbidities. For SLE-TM, initial severe neurological impairment, extensive spinal cord lesions, hyper-inflammation and delayed steroid impulse treatment could be prognosticators of poor result.
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