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Clinical features of children with enthesitis-related juvenile idiopathic arthritis/juvenile spondyloarthritis followed in a French tertiary care pediatric rheumatology centre

Pediatric Rheumatology Apr 05, 2018

Goirand M, et al. - Authors sought to ascertain the initial presentation and outcome of patients with childhood-onset spondyloarthropathies, including response to treatment, and analyze the risk factors for axial disease or active disease at the last follow up. They also assessed the proportion of patients diagnosed with Enthesitis-related arthritis (ERA) or spondyloarthritis (SpA) according to the revised Edmonton classification criteria (ILAR) and the latest Assessment of Spondylarthritis International Society (ASAS) criteria, respectively. In most patients, axial involvement developed within 5 years. For classifying patients as having childhood-onset spondyloarthropathies, revised Edmonton criteria were less sensitive than ASAS criteria. The revised ILAR classification criteria for enthesitis-related arthritis was fulfilled by 69% of patients, and 92% fulfilled the ASAS criteria for peripheral spondyolarthritis. Familial history of spondyloarthritis was the main risk factor for both sacroiliitis and persistent active disease.
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