Clinical features and molecular epidemiology of diarrheagenic Escherichia coli pathotypes identified by fecal gastrointestinal multiplex nucleic acid amplification in patients with cancer and diarrhea
Diagnostic Microbiology and Infectious Disease Aug 29, 2017
Chao A, et al. – At a major cancer center in the U.S., researchers determined clinical features and molecular epidemiology of diarrheagenic Escherichia coli pathotypes identified by fecal gastrointestinal multiplex nucleic acid amplification in patients with cancer and diarrhea. In this study, while in some instances Biofire FilmArray multiplex GI panel (BFM) results were not verified in culture and could represent false positives, diarrheagenic Escherichia coli (DEC) pathotypes, especially Enteropathogenic E. coli (EPEC) and enteroaggregative E. coli (EAEC), caused chronic infections with antimicrobial–resistant strains in a subset of immunosuppressed cancer patients.
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