Sun X, Peng M, Zhang T, et al. - Researchers investigated disparities with respect to clinical characteristics and results between microscopic polyangiitis (MPA)-associated interstitial lung diseases (ILDs) and isolated anti-neutrophil cytoplasmic antibody (ANCA)-positive idiopathic interstitial pneumonias (IIPs). This analysis involved 80 patients with ANCA-positive ILDs; MPA-ILDs were present in 31 (38.75%) and isolated ANCA-positive IIPs were present in 49 (61.25%). In multivariable analysis, erythrocyte sedimentation rate concentration was shown to be an independent risk factor for mortality in all 80 ANCA-positive ILDs cases. In this study population with ANCA-positive ILDs, findings revealed sequentially poorer prognoses for ANCA-IIPs with normal inflammation markers, ANCA-IIPs with increased inflammation markers and MPA-ILDs. Thus, considering stratified treatment in management of ILDs cases positive for ANCAs was advised.