Lv X, et al. - By retrospectively analyzing the clinical data of 34 cases of histoplasmosis hospitalized in Xiangya Hospital of Central South University from 2003 to 2016, researchers studied the clinical features and endemic trend of histoplasmosis in China to gain a better understanding of this disease. The study sample was predominantly male and included 34 patients; 44.1% were combined with underlying disease, and HIV infection was seen in 8 patients. Fever (94.1%), followed by lymphadenopathy (70.6%) and anemia (67.6%) were documented as common clinical manifestations. The organs involved were lungs (52.9%), oral cavity (5.9%) and intestine (5.9%). Amphotericin B was prescribed to 70.6%, while 38.2% received itraconazole therapy, and improvement was seen in 79.4%. Overall, histoplasmosis was viewed as a rare mycosis, which in addition to having a high diagnosis rate, demonstrated a prominent geographical distribution in China, which is recommended to be considered highly in clinical work.