Schol-Gelok S, et al. - A posthoc analysis was performed in the YEARS diagnostic study to ascertain whether D-dimer levels in patients with suspected pulmonary embolism are affected by concomitant use of antiplatelet drugs and/or statins and assessed whether the impact of antiplatelet drugs or statins might affect diagnostic accuracy. For this research, 156 statins users, 147 antiplatelet drugs users and 726 nonusers of either drug were included, all with a suspected pulmonary embolism. According to the findings obtained, use of statins but not of antiplatelet agents was associated with a modest decrease in D-dimer levels. The authors discovered that adjusting D-dimer cut-offs for statin use did, however, not result in a safer diagnostic strategy in this cohort.