Thielemans E, Oliver J, McMinn A, et al. - In this investigation involving 181 children (7 days to 16 years of age), researchers evaluated the clinical presentation, management and short- and longer-term outcomes of invasive group A streptococcal disease in children in Australia. The sample consisted of children with laboratory-confirmed invasive group A streptococcus disease admitted to 7 sentinel tertiary and quaternary pediatric hospitals in Australia between July 2016 and June 2018. Blood was the principal site of invasive infection, pneumonia in 46 children was the most frequent clinical presentation. Invasive group A streptococcal infection is frequently severe in Australian children and has a high long-term morbidity burden, demonstrating the need for strengthened clinical care pathways, epidemiological surveillance, and prevention strategies.