Jeong ID, et al. - Researchers sought to focus on the clinical course of chronic hepatitis B (CHB) patients with partial virologic response (PVR) during tenofovir disoproxil fumarate (TDF) therapy. They achieved virologic response (VR) in vast majority of CHB patients through prolonged TDF therapy, although the time to achieve VR was delayed in those with PVR. Thereby suggesting the unnecessity for adjustment of TDF therapy in patients with PVR.