Clinical course and risk factors for visual field progression in normal-tension glaucoma with myopia without glaucoma medications
American Journal of Ophthalmology Nov 13, 2019
Han JC, et al. - In this retrospective cohort study involving 97 patients, researchers analyzed the natural clinical course and the risk factors of visual field (VF) progression in untreated normal-tension glaucoma (NTG) with myopia with a minimum 3-year follow-up. To compare survival experiences between the groups, Kaplan-Meier survival analysis and log-rank test were used. Using the Cox proportional hazards model, the hazard ratios (HRs) for the relationships between potential risk factors and glaucomatous progression were determined. The average follow-up period for the patients included was 71.1 ± 29.7 months and during the observation period, 32 eyes showed progression. Even without glaucoma medications, NTG with myopia seems to have a slow progression rate. At 3 years and 5 years of follow-up in untreated NTG with myopia, respectively, 10.3% and 24.8% of patients showed VF progression. It seems that age and disc morphology should be considered in order to predict the progression of VF in untreated NTG with myopia.
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