Pines AR, et al. - Researchers conducted a retrospective chart review to report the clinical features of a single-center cohort of pediatric patients with moyamoya. The sample consisted of patients < 18 years with angiographically confirmed moyamoya disease evaluated at the institution. Fifty-one individuals met the requirements for inclusion. Data reported that nearly half of the patients had bilateral disease. Sixteen individuals had a genetic or chromosomal diagnosis (Down syndrome and NF1 being most common). Congenital anomalies such as heart defects and renal dysplasia were also recorded. This research is unusual in that it was a large study performed on pediatric patients with moyamoya angiopathy. In addition, it highlights the significance of considering genetic syndromes as an underlying cause when moyamoya angiopathy starts early in life.