Uwaydat SH, Mansour A, Ascaso FJ, et al. - In this investigation involving 78 patients (mean age 57.9 years), researchers sought to determine the anatomic factors that help achieve non-surgical sealing in full thickness macular hole (FTMH). It was a retrospective collaborative study of FTMH that closed without surgical intervention. Participants in the study were 18 patients with blunt ocular trauma, 18 patients that received topical or intravitreal therapies and 42 patients with idiopathic FTMH. The data suggest a period of observation in new-onset FTMH for non-surgical closure, in the setting of trauma, treatment of cystoid macular oedema and size < 200 µm.