Villatoro-Villar M, et al. - In this investigation involving 243 patients, researchers outlined the differences in clinical features and outcome between adult- and childhood-onset biopsy-proven IgA vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, in North America. From January 1, 1997, through December 31, 2016, patients with IgAV diagnosed were retrospectively identified. To estimate survival rates, Kaplan-Meier methods were utilized. Patients with IgAV were included in this analysis. In adults, IgA vasculitis is linked to greater involvement of the skin/kidney and poorer renal outcome. At diagnosis, patients aged 51 years or older had a significantly higher risk of death compared with the general population, mostly due to malignancy. Data reported that 5-year survival rates were 100%, 94%, and 40%, respectively, for patients younger than 21, 21 to 50, and 51 years of age or older.