Clinical characteristics and viral RNA detection in children With coronavirus disease 2019 in the Republic of Korea
JAMA Sep 02, 2020
Han MS, Choi EH, Chang SH, et al. - Researchers sought to describe the complete clinical course and the duration of SARS-CoV-2 RNA detectability in children confirmed with COVID-19 in the Republic of Korea, where implementation of rigorous public health interventions has been done. At 20 hospitals and 2 nonhospital isolation facilities in Korea, they conducted this case series of 91 children younger than 19 years who had COVID-19. Among these cases, 22.0% were asymptomatic. Diagnosis of only 8.5% of symptomatic cases was done at the time of symptom onset, while there were unrecognized symptoms in 66.2% before diagnosis and symptoms development was noted in 25.4% after diagnosis; SARS-CoV-2 RNA was identified for a mean of 17.6 days overall and 14.1 days in asymptomatic cases. Per these findings, most COVID-19 cases in children could not be identified with symptom screening, and detection of SARS-CoV-2 RNA in children occurred for an unexpectedly long time.
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