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Clinical characteristics and viral RNA detection in children with coronavirus disease 2019 in the Republic of Korea

JAMA Pediatrics Jan 07, 2021

Han MS, Choi EH, Chang SH, et al. - Researchers conducted the study for analyzing the full clinical course and the duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA detectability in children confirmed with coronavirus disease 2019 (COVID-19) in the Republic of Korea, where rigorous public health measures have been introduced. Data reported that 22.0% were asymptomatic in this case series of 91 children (median [range] age, 11 [0-18] years; 53 boys [58%]) with COVID-19 in Korea. No difference was found in the duration of virus RNA detection between children with upper respiratory tract infections and lower respiratory tract infections. In this case series study, inapparent infections in children may have been related to the silent transmission of COVID-19 in the community. Increased laboratory screening surveillance will allow for the detection of children with unrecognized SARS-CoV-2 infection.

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