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Clinical characteristics and therapeutic outcomes of metastatic peritoneal carcinomatosis in non-small-cell lung cancer

Cancer Management and Research Oct 01, 2021

Tani T, Nakachi I, Ikemura S, et al. - A poor prognosis of metastatic peritoneal carcinomatosis (MPC) was evident in non-small cell lung cancer (NSCLC) patients who received only the best supportive care, however, an improved prognosis may be achieved with therapeutic intervention.

  • A total of 46 NSCLC patients with MPC were included and retrospectively investigated.

  • The profile of histological subtype was mainly adenocarcinoma and presence of driver oncogenes was found in 15 patients.

  • Performance status and the presence of a driver oncogene were significantly related to prolonged overall survival (OS).

  • Significantly longer median OS was observed in the treatment group (9.3 months) vs in the best supportive care group (1.3 months).

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