de Bonnecaze G, et al. - Authors conducted a multicenter, collaborative study to evaluate treatment strategy, oncological outcome, and prognostic factors in a group of patients with sinonasal undifferentiated carcinoma (SNUC). The prognosis of SNUC could be improved with multimodal therapies, including induction chemotherapy and intensity-modulated radiotherapy. Local control could be improved via surgery. In the multivariate analyses, only induction chemotherapy was significantly associated with improved RFS.