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Clinical characteristics and outcome of primary brain abscess: A retrospective analysis

BMC Infectious Diseases Dec 17, 2021

Huang J, Wu H, Huang H, et al. - The demographic, laboratory, and neuroimaging features of patients with brain abscess are investigated and factors linked with their outcomes are described.

  • Of 57 patients diagnosed with primary abscess at researchers’ hospital between January 2011 and December 2020, 51 (89.47%) were older than 40 years, and 42 (73.68%) were male.

  • Overall, there appeared higher susceptibility to brain abscess among male patients and those older than 40 years when compared with female patients and those younger than 40 years, respectively.

  • The classical triad of clinical symptoms was observed in only a few patients.

  • The most common comorbidity was diabetes mellitus.

  • Results of intracranial specimen culture were uncommonly positive; the main organisms found were gram-negative enteric bacteria, especially Klebsiella pneumoniae.

  • In 54.39% of the patients, management included surgical treatment, most commonly in the form of stereotactic drainage.

  • Mostly good outcomes were achieved in patients.

  • More frequently, patients with headaches have a poor outcome

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