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Clinical characteristics and oncological outcomes in negative multiparametric MRI patients undergoing robot-assisted radical prostatectomy

The Prostate Jun 05, 2021

Wagaskar VG, Ratnani P, Levy M, et al. - In this retrospective analysis, the researchers sought to analyze clinical parameters and oncological outcomes in men with negative mpMRI (nMRI; PI-RADS v2 scores of ≤ 2) who underwent robot-assisted radical prostatectomy (RARP) to assess nMRI's practicality as a biopsy triage test. The sample consisted of 331 men with nMRI who had RARP between 2014 and 2020 compared with men with positive mpMRI (pMRI; PI-RADS v2 scores ≥ 3, N = 1,770). Men with nMRI present diagnostic challenges because they are younger patients with lower rates of suspicious digital rectal examination findings and lower 4K scores but comparable oncological outcomes in terms of clinically significant prostate cancer rates, positive surgical margins, and biochemical recurrence rates.

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