Mehren C, et al. - In this nonrandomized, prospective, and single-center clinical trial, investigators assessed 55 individuals to estimate the clinical and radiological consequences of refined total cervical disc replacement (cTDR), the ProDisc Vivo, with 2 years of follow-up (FU). They recorded an overall improvement in the Neck Disability Index (NDI), Visual Analogue Scale (VAS), arm and neck/arm pain. They noticed heterotopic ossifications at the index segment as follows: grade 0 in 58%, grade 1 in 22%, grade 2 in 10%, grade 3 (with functional impairment of the prosthesis) in 7%, and grade 4 in 3% of the cases. They assumed that less invasive implantation mechanism with lower primary stability of the cTDR might be a cause for a higher dislocation rate as compared to the keel-based previous generation ProDisc C.