Dufour T, et al. - Three hundred and eighty-four individuals were treated using Mobi-C cervical disc (Zimmer Biomet, Troyes, France) and involved in a prospective multicentre study by the researchers in order to give 5-year follow-up outcomes of an ongoing prospective study following implantation of cervical disc prosthesis. Results at 5 years exhibited notable improvement in all clinical outcomes (Neck Disability Index, a visual analogue scale for arm and neck pain, Survey Short Form-36 physical component scores (PCS) and mental CS). From 6.0° preoperatively to 8.0°, motion at index level increased markedly, and 72.1% of the implanted segments were still mobile. In comparison with baseline, proximal and distal adjacent discs demonstrated no marked variation in average motion 5 years following surgery. In 16.4% of the implanted segments, ossification leading to complete fusion was noted. In 42.2% and 39.1% of patients, respectively, the occurrence of distal and proximal adjacent disc degeneration was observed. Complications rate was 8.9%, and at the index level, 1.5% of the individuals had reoperation. For adjacent discs, the surgery rate was 2.9%. An elevated percentage of working individuals and a reduction in medication intake were discovered. Relative to the overall outcome 93.3% of patients were satisfied, at 5 years. Hence, with a low rate of adjacent level surgery, favorable 5-year follow-up clinical and radiological results were recognized in this study.