Clarifying the role of C-reactive protein as a bacterial infection predictor in decompensated cirrhosis
European Journal of Gastroenterology & Hepatology May 03, 2018
Perdigoto DN, et al. - Experts attempted to investigate the role of ultrasensitive C-reactive protein (US-CRP) as an infection predictor in decompensated cirrhosis. It was discovered that Escherichia coli was the most frequently isolated bacteria. In contrast with the no infection group, US-CRP levels were markedly higher in cases of overt infection and positive culture groups. Findings reported that the ideal US-CRP infection confirmatory cutoff appeared to be situated between 2.40 and 3.92 mg/dl. Since infection was concealed and hazardous in cirrhotic patients, if not considered with lower US-CRP levels according to specific clinic scenarios, cautious consideration was required, if US-CRP was greater than 2.40 mg/dl (0.5 mg/dl normal upper cutoff).
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