Zhao Q, et al. - Whether admission macrophage migration inhibitory factor (MIF) levels could serve as a valuable predictor of clinical outcomes in ST-elevation MI (STEMI) patients was investigated in this study. Researchers analyzed 498 STEMI patients after percutaneous coronary intervention (PCI), 40 with stable angina pectoris, and 137 healthy subjects. At admission and after PCI, plasma MIF levels were measured. In STEMI patients who underwent PCI, in-hospital mortality and long-term major adverse cardio- and cerebro-vascular events were independently predicted by a higher admission MIF level. MIF levels at admission were higher in 88.4% STEMI patients over the upper reference limit of healthy controls and they were significantly higher in patients who died after MI vs survivors.