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Circulating microRNAs as biomarkers for diagnosis and prediction of preeclampsia: A systematic review and meta-analysis

European Journal of Obstetrics & Gynecology and Reproductive Biology Aug 28, 2020

Yin Y, Liu M, Yu H, et al. - Via performing a meta-analysis, researchers sought to quantitatively delineate the overall diagnostic and predictive effects of circulating microRNAs in diagnosis and prediction of preeclampsia, respectively. Eight articles comprising 273 preeclampsia patients and 343 normal pregnancies were included in this meta-analysis. Outcomes suggest relatively high diagnostic and predictive accuracy of circulating miRNAs in distinguishing patients with preeclampsia from controls. Thus they support circulating miRNAs as a valuable screening tool to diagnose and predict preeclampsia.

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