Xie SH, Rabbani S, Ness-Jensen E, et al. - Researchers estimated links between 13 obesity-related inflammatory and metabolic biomarkers and risk of esophageal adenocarcinoma (EAC) or Barrett's esophagus (BE). For this purpose, they explored MEDLINE and EMBASE until October 2018. This analysis involved 19 eligible studies out of 7,641 identified studies. Experts analyzed 12 cross-sectional, 2 nested case-control and 5 cohort studies. According to the findings, an increased risk of EAC or BE may exist in correlation with higher circulating levels of leptin, glucose, insulin, C-reactive protein, interleukin 6 and soluble tumor necrosis factor receptor 2.