Bernard H, Turner PJ, Ah‐Leung S, et al. - Given that a crucial determinant of allergic reactions may be bioaccessibility of food allergens, researchers created a protocol enabling the identification of the major peanut allergen, Ara h 6 (a peanut 2S albumin), in the bloodstream after ingestion of low amounts of peanut and they sought to compare Ara h 6 bioaccessibility by food matrix. They further evaluated for disparities in absorption in healthy vs peanut‐allergic volunteers. A blood pretreatment integrating acidic shock and thermal treatment was developed. Optimization of an original pretreatment protocol led to irreversible dissociation of human antibodies‐Ara h 6 immune complex, therefore rendering Ara h 6 accessible for its immunodetection. Overall, findings showed the dependence of kinetics as well as intensity of Ara h 6 passage in bloodstream on both individual and food matrix. Peanut‐allergic patients seemed to show higher absorption rate, the clinical importance of which warrants further assessment.