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Chronic prescription opioid use predicts stabilization on buprenorphine for the treatment of opioid use disorder

Journal of Substance Abuse Treatment Jul 01, 2020

Varisco T, et al. - Researchers investigated the adjusted odds of successful stabilization on buprenorphine in cases with baseline prescription opioid use compared with those not prescribed opioids. From the Texas prescription monitoring program, they identified a cohort of patients 6,756 eligible patients who were newly prescribed a buprenorphine product indicated for OUD between January 1 and November 30, 2018. Among these patients, 44.1% used prescription opioids in the 90 days prior to buprenorphine initiation. Findings revealed varying baseline prescription opioid use among persons taking buprenorphine for OUD. Demographic variation was reported among patients with prior opioid prescriptions vs those without. More frequently, patients with prescription opioid use at baseline were older and were insured compared with those with no prescription opioid use. Prior prescription opioid use was predictive of stabilization on buprenorphine. Tendency for stabilization was utmost among patients with chronic prescription opioid use.

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