Filler G, et al. - In view of the fact that young adult and paediatric patients have shorter exposure to Framingham-type risk factors, this study investigated if younger chronic kidney disease (CKD) patients exhibit the same small, dense low-density lipoprotein (sd-LDL) and glycated LDL (g-LDL) pattern as seen in CKD patients >60 years of age. Findings revealed an association of only triglycerides and sd-LDL with CKD stages in this young cohort without confounding Framingham-type cardiovascular disease (CVD) risk factors. Data indicated that in order to ameliorate the long-term CVD risks in paediatric CKD patients, lowering sd-LDL levels may be a potential target.