George C, Matsha TE, Davidson FE, et al. - In this study with South Africans of mixed-ancestry (n = 1,621), researchers examined the link between adiposity and blood pressure (BP) by chronic kidney disease (CKD) status. Estimated glomerular filtration rate was based on the alteration of diet in renal disease equation. By performing anthropometry [body mass index (BMI) and waist circumference (WC)] and dual-energy x-ray absorptiometry (n=152), experts evaluated body fat distribution. The overall sample showed independent link of only BMI and WC with systolic blood pressure, diastolic blood pressure and mean arterial pressure in the multivariable analysis. A rise in BP was generally evident with increasing measures of adiposity in individuals without CKD. However, in patients with CKD, a likely protective or neutral effect of excess body fat on BP was concluded.