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Chronic kidney disease increases the risk of hip fracture: a prospective cohort study in korean adults

Journal of Bone and Mineral Research Mar 28, 2020

Kim SH, et al. - This study intended to analyze whether renal function associated with hip fracture. During 2009–2010 until 2013, researchers followed up 352,624 Korean adults, who included in health examinations. Via creatinine‐based estimated glomerular filtration rate (eGFR) and albuminuria using urine reagent strip results, kidney function was investigated.  The hospital discharge records examined the incidence of hip fracture. They estimated hazard ratios (HRs) for hip fracture applying Cox proportional hazard models after adjusting for multiple confounders. It was noted that 1177 participants suffered a hip fracture during a mean follow‐up of 4.0 years. In Korean adults, both low eGFR and albuminuria were found to be risk factors for incident hip fracture. Furthermore, these factors exerted a synergistic impact on the risk of hip fracture. 

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