Chronic kidney disease and HIV in the era of antiretroviral treatment: Findings from a 10-year cohort study in a west African setting
BMC Nephrology May 10, 2019
Kaboré NF, et al. - In a large cohort of HIV-patients (n=3,138, 72% women) in Burkina Faso who were assessed over a median of 4.5 years, researchers determined the frequency of chronic kidney disease (CKD) as well as any alterations in kidney function during antiretroviral treatment (ART). Findings revealed a 0.5% prevalence of CKD and 1.9 [1.3; 2.7] cases/1,000 person-years was the incidence. Those with high blood pressure (HBP), patients 40-49 years old, patients ≥50 years old, and patients exposed to abacavir or didanosine based ART had a higher risk of CKD. The high risk of CKD reported in previous studies of West Africans with HIV was not corroborated in this study but early initiation of ART and close kidney function monitoring in patients with HBP or aged ≥40 years was supported by the findings.
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