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Chronic kidney disease and acute kidney injury in arthroplasty patients over 65 years of age

Acta Anaesthesiologica Scandinavica Mar 26, 2019

Nikkinen O, et al. - In this retrospective, hospital register-based study of primary arthroplasty patients over 65 years of age, researchers assessed the prevalence of chronic kidney disease (CKD) and the incidence of perioperative acute kidney injury (AKI) as well as evaluated risk factors, perioperative events and surgical outcomes. This study included patients who underwent surgery in 2014 in the area of Oulu, Finland. Overall 807 patients were included, of those, mildly decreased (60-89 ml/min/1.73 m2) and moderately to severely decreased estimated glomerular filtration rate (eGFR)(<60 ml/min/1.73 m2) were detected preoperatively in 60.8% and 13.5%, respectively. They found a common prevalence of kidney function impairment, which was associated with mortality in emergency arthroplasties. High risk patients got their postoperative sCr measured. Significant determinants for perioperative AKI were preoperative kidney function, kidney disease and diabetes mellitus.
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