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Chronic hepatitis B virus infection and risk of chronic kidney disease: A population-based prospective cohort study of 0.5 million Chinese adults

BMC Medicine Jun 21, 2018

Si J, et al. - Researchers prospectively investigated the relationship between chronic hepatitis B virus (HBV) infection and chronic kidney disease (CKD) risk, and the joint associations of HBV infection with established risk factors of several lifestyle factors and prevalent diseases on CKD risk. They involved members from the China Kadoorie Biobank during 2004–2008 and followed up until 31 December 2015. This study comprised 469,459 participants. They found that kidney damage associated with chronic HBV infection should be a non-negligible concern in countries with a high endemicity of HBV infection. In addition, this investigation highlighted the importance of health advice on quitting smoking, increasing physical activity, improving glucose control, and early screening for CKD in people with chronic HBV infection.
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