Chronic diseases in the children of women with maternal thyroid dysfunction: A nationwide cohort study
Clinical Epidemiology Oct 07, 2018
Jølving LR, et al. - Researchers conducted a register-based cohort study on all children born live in Denmark from 1989 to 2013 to assess the relationship between maternal thyroid disease (TD) during pregnancy and somatic and psychiatric diseases in the children to investigate if they have increased disease risk during childhood and adolescence. In childhood and adolescence, children born to women with Graves’ disease and Hashimoto’s thyroiditis have greater long-term morbidities. In particular, an increased risk of any TD and type 1 diabetes was found in children exposed in utero to Graves’ disease. When evaluating children with suspected endocrine disorders, these novel findings focusing on the significance of the history of a maternal disease are significant.
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