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Chronic administration of myristic acid improves hyperglycaemia in the Nagoya–Shibata–Yasuda mouse model of congenital type 2 diabetes

Diabetologia - Clinical and Experimental Diabetes and Metabolism Sep 16, 2017

Takato T, et al. - The point of this study was to analyze the glucose-lowering impact of myristic acid in Nagoya–Shibata–Yasuda (NSY) mice, a spontaneous model for studying obesity-related type 2 diabetes. These outcomes this study highlighted that the chronic oral administration of myristic acid enhances hyperglycaemia by decreasing insulin-responsive glucose levels and reducing body weight, and that the fatty acid accounts for the diabetes protective properties of high-fat dairy products. It was considered that myristic acid is a potential candidate for the prevention and treatment of type 2 diabetes mellitus and its related diseases.
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