Childhood overweight, tallness and growth increase risks of ovarian cancer
Cancer Epidemiology, Biomarkers & Prevention Oct 04, 2018
Aarestrup J, et al. - Whether childhood body mass index, height, and growth patterns were related to ovarian cancer overall and by histologic subtypes was investigated in a cohort of 155,958 girls from the Copenhagen School Health Records Register, born 1930-1989 with measured weights and heights from 7-13 years. Findings revealed increased risks of ovarian cancer overall, mucinous, endometrioid and clear cell ovarian cancers, but not serous and other ovarian cancers, in overweight girls at most ages vs non-overweight girls. Positive and significant links were seen between childhood height and ovarian cancer overall and the endometrioid subtype, but not with the other subtypes. Overall, there is a relationship between ovarian carcinogenesis and childhood overweight, tallness and growth that varies across histological subtypes.
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