El-Khoury F, Rieckmann A, Bengtsson J, et al. - Using a register-based Danish cohort, researchers intended to determine if there is a correlation between trajectories of childhood adversities and post-traumatic stress disorder (PTSD). According to childhood adversity trajectories from age 0 to 16 (n= 1,277,548), they calculated the prevalence of PTSD diagnosed from age 16. Low Adversity, Early Life Material Deprivation, Persistent Material Deprivation, Loss or Threat of Loss, and High Adversity were the five trajectories defined previously. Children exposed to childhood adversity had a higher likelihood of being diagnosed with PTSD vs the low adversity group. In both men and women, relative associations were comparable, though nearly twice as many women were affected as men. A strong link between exposure to childhood adversities and PTSD in young adulthood was documented, with women in the high-adversity group having the greatest burden.