Godinho-Mota JCM, Mota JF, Gonçalves LV, et al. - In women with newly diagnosed with stage II–III breast cancer (2014–18), researchers conducted this prospective study to assess the effect of chemotherapy (CT) on body composition, bone mineral density (BMD), insulin resistance, lipid markers related to atherosclerotic cardiovascular diseases according to menopausal status. Ninety-nine women (40.4% in the premenopausal stage) aged 51 ± 1 years participated in this research. According to the findings, breast cancer CT negatively affected body composition and metabolic profile. CT was linked with an increase in total and central adiposity, insulin resistance, and all lipid-related markers, and a decrease in appendicular lean mass index, BMD and HDL-c concentration. The adverse effect on adiposity markers and BMD was greater in premenopausal women. No changes in dietary intake and post-CT physical activity were observed.