Elder K, et al. - This study is planned to assess the pharmacokinetics of vancomycin dosing in thermal or inhalation injury as they relate to percent total body surface area burn (TBSA) and days since injury (DSI). Authors suggest that DSI, percent TBSA, and Creatinine clearance (CrCl) may be predictive of faster vancomycin CL and need for higher total daily doses. Findings suggest the occurrence of augmented pharmacokinetics as early as two days after an injury that decreases with time. Acceptable target trough attainment is still lacking. Therefore, for initial vancomycin dosing, this data should assist in performance improvements.