Li L, Zhou Z, Xiong W, et al. - In the present study, the researchers used multivariate analysis of T2-weighted signal, diffusion ADC, and DKI parameters and tractography to distinguish chronic non-specific low back pain (CLBP) individuals and asymptomatic controls (AC). In total, 30 patients with CLBP and 23 AC had diffusion kurtosis imaging (DKI) of the lumbar spine with a 3T MRI scanner to get the ADC values and seven parameters of DKI in the nucleus pulposus (NP) of the intervertebral disc. No difference was found in the T2 grades, ADC value, and multiple parameters in DKI of NP between CLBP and AC groups. Findings suggested that DKI is a good non-invasive approach and may help distinguish between CLBP and AC. The continuation of DKI tractography, in particular, represents the existence of annulus fibrosus fissures, an important character in low back pain generation.