Chan KM, et al. - This retrospective review gathered experience with surgical treatment for intrahepatic cholangiocarcinoma (ICC) and aimed at analyzing the prognosis of patients who had received curative-intent liver resection. Study participants included 216 patients who had undergone curative-intent liver resection for ICC between January 1977 and December 2014. The general outcome of patients with ICC is still unsatisfactory due to a high incidence of cholangiocarcinoma recurrence after operation despite curative resection. For the prognosis of patients with ICC after curative liver resection, tumor factors associated with cholangiocarcinoma remain crucial. In addition, an aggressive attitude towards repeated resection for postoperative recurrent cholangiocarcinoma could be beneficial for patients.