Jang Y, et al. - In this retrospective analysis of 126 patients who were treated for stage III gastric cancer from Jan. 2007 to Dec. 2010 at Korea University Hospital and were followed-up for 5 years, researchers assessed the prognostic factors. Patients who survived more than five years after gastrectomy were considered as long-term survivors. There were 70 (55.6%) long-term survivors. Univariate analysis revealed prognostic significance for tumor size, lymph node involvement, lymphatic invasion, venous invasion and neural invasion. Peritoneal recurrence (57.4%) was the most common recurrence pattern. Based on recurrence pattern, the disease specific survival was peritoneal recurrence (9.2 months), hematogenous recurrence (11.3 months), distant lymph node recurrence (16.2 months) and locoregional (26.9 months). The most significant prognostic factors on stage III gastric cancer after curative resection were lymph node involvement and due to this, extreme care was exercised when postoperative surveillance and adjuvant therapy were selected in stage III gastric cancer patient with extensive lymph node metastasis.