Troger T, Sommer G, Lang-Muritano M, et al. - When reassessed during pubertal years, patients with and without significant bone age advancement, and thus differing height prediction during adrenarche, had similar (predicted) final height. Bone age alone should not be used as a clinical marker for metabolic control in congenital adrenal hyperplasia (CAH) treatment during adrenarche.

• Participants in the study were 41 patients with classical CAH, born between 1990 and 2012.

• Patients with classic CAH were significantly shorter than their peers and parents.

• Growth patterns during adrenarche revealed two distinct growth patterns: patients with accelerating bone age (49%) and patients with non-accelerating bone age compared with chronological age (BA-CA).

• Patients with accelerating BA-CA were taller than the general population during adrenarche years and were predicted to have a lower adult height SDS than non-accelerating patients.

• Both the accelerating and non-accelerating BA-CA groups had similar reductions in final adult height.